D-Biotin
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Biotin, also known as vitamin H or coenzyme R, is a water-soluble B-vitamin (vitamin B7).
It is composed of a ureido (tetrahydroimidizalone) ring fused with a tetrahydrothiophene ring. A valeric acid substituent is attached to one of the carbon atoms of the tetrahydrothiophene ring. Biotin is a coenzyme for carboxylase enzymes, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis.
D-Biotin / Vitamin H
C.A.S NO. : 58-85-5
Synonyms: Vitamin B7, Coenzyme R
EINECS NO.: 200-399-3
Molecular formula: C10H16N2O3S
Molecular weight : 244.31
Assay: 99%, 2%, 1%
Characteristic: White or off-white crystalline powder
Melting point: 231-233℃
Solubility: Water soluble
Application
1.Hair problems:
Biotin supplements are often recommended as a natural product to counteract the problem of hair loss in both children and adults. The signs and symptoms of biotin deficiency include hair loss which progresses in severity to include loss of eye lashes and eye brows in severely deficient subjects. Some shampoos are available that contain biotin, but it is doubtful whether they would have any useful effect, as biotin is not absorbed well through the skin.
2.Cradle Cap (Seborrheic Dermatitis):
Children with a rare inherited metabolic disorder called phenylketonuria (PKU; in which one is unable to break down the amino acid phenylalanine) often develop skin conditions such as eczema and seborrheic dermatitis in areas of the body other than the scalp. The scaly skin changes that occur in people with PKU may be related to poor ability to use biotin. Increasing dietary biotin has been known to improve seborrheic dermatitis in these cases.
3.Diabetes:
Diabetics may also benefit from biotin supplementation. In both insulin-dependent and non-insulin-dependent diabetes, supplementation with biotin can improve blood sugar control.